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Chemical structure of MAC glucuronide linker-2

GC38924

MAC glucuronide linker-2

Also known as methyl (2S,3S,4S,5R,6S)-3,4,5-triacetyloxy-6-[2-amino-4-(hydroxymethyl)phenoxy]oxane-2-carboxylate

MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

ChemicalCAS229977-57-5MW455.41FormulaC20H25NO11
CAS number
229977-57-5
Molecular weight
455.41
Formula
C20H25NO11
Solubility
DMSO： 200 mg/mL (439·16 mM)
InChIKey
ZAZPQJAJSIUIEY-KVIJGQROSA-N
Catalogue number
GC38924
Brand
GLPBIO
Computed properties PubChem CID 59816530 · XLogP -0.1 · TPSA 170 Ų · H-bond donors 2
XLogP
-0.1
TPSA
170 Ų
H-bond donors
2
H-bond acceptors
12
Rotatable bonds
11
Heavy atoms
32

SMILES CC(=O)O[C@H]1[C@@H]([C@H](O[C@H]([C@@H]1OC(=O)C)OC2=C(C=C(C=C2)CO)N)C(=O)OC)OC(=O)C

Computed descriptors from PubChem (CID 59816530), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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