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Chemical structure of KY-226

GC38919

KY-226

Also known as N-hexylsulfonyl-4-[(4-phenylphenyl)methylsulfanylmethyl]benzamide

KY-226 is a potent, selective, orally active and allosteric protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 of 0·25 μM, and without PPARγ agonist activity

ChemicalCAS1621673-53-7MW481.67FormulaC27H31NO3S2
CAS number
1621673-53-7
Molecular weight
481.67
Formula
C27H31NO3S2
Solubility
DMSO: 250 mg/mL (519·03 mM)
InChIKey
MKXMABKUVSOEJF-UHFFFAOYSA-N
Catalogue number
GC38919
Brand
GLPBIO
Computed properties PubChem CID 76955652 · XLogP 6.7 · TPSA 96.9 Ų · H-bond donors 1
XLogP
6.7
TPSA
96.9 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
12
Heavy atoms
33

SMILES CCCCCCS(=O)(=O)NC(=O)C1=CC=C(C=C1)CSCC2=CC=C(C=C2)C3=CC=CC=C3

Computed descriptors from PubChem (CID 76955652), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.