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Chemical structure of CCG-222740

GC38898

CCG-222740

Also known as N-(4-chlorophenyl)-5,5-difluoro-1-[3-(furan-2-yl)benzoyl]piperidine-3-carboxamide

CCG-222740 is an orally active and selective Rho/myocardin-related transcription factor (MRTF) pathway inhibitor· CCG-222740 is also a potent inhibitor of alpha-smooth muscle actin protein expression· CCG-222740 effectively reduces fibrosis in skin and blocks melanoma metastasis

ChemicalCAS1922098-69-8MW444.86FormulaC23H19ClF2N2O3
CAS number
1922098-69-8
Molecular weight
444.86
Formula
C23H19ClF2N2O3
Solubility
DMSO: 125 mg/mL (280·99 mM); Water: < 0·1 mg/mL (insoluble)
InChIKey
PMTPYUTZAJWGPE-UHFFFAOYSA-N
Catalogue number
GC38898
Brand
GLPBIO
Computed properties PubChem CID 121317937 · XLogP 4.4 · TPSA 62.6 Ų · H-bond donors 1
XLogP
4.4
TPSA
62.6 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
31

SMILES C1C(CN(CC1(F)F)C(=O)C2=CC=CC(=C2)C3=CC=CO3)C(=O)NC4=CC=C(C=C4)Cl

Computed descriptors from PubChem (CID 121317937), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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