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Chemical structure of XL-784 free base

GC38871

XL-784 free base

Also known as 2-methoxyethyl 4-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-3-(hydroxycarbamoyl)piperazine-1-carboxylate

XL-784 free base is a selective matrix metalloproteinases (MMP) inhibitor, with IC50s of ~1900, 0·81, 120, 10·8, 18, 0·56 nM for MMP-1, MMP-2, MMP-3, MMP-8, MMP-9 and MMP-13, respectively

ChemicalCAS1356992-21-6MW549.93FormulaC21H22ClF2N3O8S
CAS number
1356992-21-6
Molecular weight
549.93
Formula
C21H22ClF2N3O8S
Solubility
DMSO： 250 mg/mL (454·60 mM)
InChIKey
PRIJGYZAOBNIPH-UHFFFAOYSA-N
Catalogue number
GC38871
Brand
GLPBIO
Computed properties PubChem CID 74439626 · XLogP 1.8 · TPSA 143 Ų · H-bond donors 2
XLogP
1.8
TPSA
143 Ų
H-bond donors
2
H-bond acceptors
11
Rotatable bonds
9
Heavy atoms
36

SMILES COCCOC(=O)N1CCN(C(C1)C(=O)NO)S(=O)(=O)C2=CC(=C(C(=C2)F)OC3=CC=C(C=C3)Cl)F

Computed descriptors from PubChem (CID 74439626), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.