GC38864
TL02-59
Also known as 3-(6,7-dimethoxyquinazolin-4-yl)oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide
TL02-59 is an orally active, selective Src-family kinase Fgr inhibitor with an IC50 of 0·03 nM· TL02-59 inhibits Lyn and Hck with IC50s of 0·1 nM and 160 nM, respectively· TL02-59 potently suppresses acute myelogenous leukemia (AML) cell growth
ChemicalCAS1315330-17-6MW609.64FormulaC32H34F3N5O4
- CAS number
- 1315330-17-6
- Molecular weight
- 609.64
- Formula
- C32H34F3N5O4
- Solubility
- DMSO： 125 mg/mL (205·04 mM)
- InChIKey
- AMHWQBGAKJESFB-UHFFFAOYSA-N
- Catalogue number
- GC38864
- Brand
- GLPBIO
Computed properties PubChem CID 71254350 · XLogP 5.4 · TPSA 89.1 Ų · H-bond donors 1
- XLogP
- 5.4
- TPSA
- 89.1 Ų
- H-bond donors
- 1
- H-bond acceptors
- 11
- Rotatable bonds
- 9
- Heavy atoms
- 44
SMILES CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=NC=NC5=CC(=C(C=C54)OC)OC)C(F)(F)F
Computed descriptors from PubChem (CID 71254350), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il