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Chemical structure of Tandutinib hydrochloride

GC38853

Tandutinib hydrochloride

Also known as 4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-(4-propan-2-yloxyphenyl)piperazine-1-carboxamide;hydrochloride

Tandutinib hydrochloride (MLN518 hydrochloride) is a potent and selective inhibitor of the FLT3 with an IC50 of 0·22 μM, and also inhibits c-Kit and PDGFR with IC50s of 0·17 μM and 0·20 μM, respectively· Tandutinib hydrochloride can be used for acute myelogenous leukemia (AML)· Tandutinib hydrochloride has the ability to cross the blood-brain barrier

ChemicalCAS2438900-70-8MW599.16FormulaC31H43ClN6O4
CAS number
2438900-70-8
Molecular weight
599.16
Formula
C31H43ClN6O4
Solubility
DMSO： ≥ 100 mg/mL (166·90 mM); Water： 100 mg/mL (166·90 mM)
InChIKey
FOEBHLNUCNUHHJ-UHFFFAOYSA-N
Catalogue number
GC38853
Brand
GLPBIO
Computed properties PubChem CID 138911453 · TPSA 92.3 Ų · H-bond donors 2 · H-bond acceptors 8
TPSA
92.3 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
10
Heavy atoms
42

SMILES CC(C)OC1=CC=C(C=C1)NC(=O)N2CCN(CC2)C3=NC=NC4=CC(=C(C=C43)OC)OCCCN5CCCCC5.Cl

Computed descriptors from PubChem (CID 138911453), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.