GC38807
Lapaquistat acetate
Also known as 2-[1-[2-[(3R,5S)-1-(3-acetyloxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-5H-4,1-benzoxazepin-3-yl]acetyl]piperidin-4-yl]acetic acid
Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor, blocking the conversion of farnesyl diphosphate (FPP) to squalene in the cholesterol biosynthesis pathway
ChemicalCAS189060-13-7MW645.14FormulaC33H41ClN2O9
- CAS number
- 189060-13-7
- Molecular weight
- 645.14
- Formula
- C33H41ClN2O9
- Solubility
- DMSO： 46 mg/mL (71·30 mM)
- InChIKey
- CMLUGNQVANVZHY-POURPWNDSA-N
- Catalogue number
- GC38807
- Brand
- GLPBIO
Computed properties PubChem CID 9874248 · XLogP 3.8 · TPSA 132 Ų · H-bond donors 1
- XLogP
- 3.8
- TPSA
- 132 Ų
- H-bond donors
- 1
- H-bond acceptors
- 9
- Rotatable bonds
- 12
- Heavy atoms
- 45
SMILES CC(=O)OCC(C)(C)CN1C2=C(C=C(C=C2)Cl)[C@H](O[C@@H](C1=O)CC(=O)N3CCC(CC3)CC(=O)O)C4=C(C(=CC=C4)OC)OC
Computed descriptors from PubChem (CID 9874248), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il