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Chemical structure of CKI-7

GC38755

CKI-7

Also known as N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide

CKI-7 is a potent and ATP-competitive casein kinase 1 (CK1) inhibitor with an IC50 of 6 μM and a Ki of 8·5 μM· CKI-7 is a selective Cdc7 kinase inhibitor· CKI-7 also inhibits SGK, ribosomal S6 kinase-1 (S6K1) and mitogen- and stress-activated protein kinase-1 (MSK1)· CKI-7 has a much weaker effect on casein kinase II and other protein kinases

ChemicalCAS120615-25-0MW285.75FormulaC11H12ClN3O2S
CAS number
120615-25-0
Molecular weight
285.75
Formula
C11H12ClN3O2S
Solubility
DMSO： 25 mg/mL (87·49 mM)
InChIKey
OGKYMFFYOWUTKV-UHFFFAOYSA-N
Catalogue number
GC38755
Brand
GLPBIO
Computed properties PubChem CID 129236 · XLogP 0.8 · TPSA 93.5 Ų · H-bond donors 2
XLogP
0.8
TPSA
93.5 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
18

SMILES C1=CC(=C2C=CN=CC2=C1S(=O)(=O)NCCN)Cl

Computed descriptors from PubChem (CID 129236), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.