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Chemical structure of AR-C102222 hydrochloride

GC38735

AR-C102222 hydrochloride

Also known as 5-(4-amino-5,8-difluorospiro[1H-quinazoline-2,4'-piperidine]-1'-carbonyl)pyridine-2-carbonitrile;hydrochloride

AR-C102222 hydrochloride is a potent, competitive, orally active and highly selective inducible nitric oxide synthase (iNOS) inhibitor, with an IC50 of 37 nM

ChemicalCAS1781934-50-6MW418.83FormulaC19H17ClF2N6O
CAS number
1781934-50-6
Molecular weight
418.83
Formula
C19H17ClF2N6O
Solubility
Soluble in DMSO
InChIKey
FJFMOBYDHGJDGV-UHFFFAOYSA-N
Catalogue number
GC38735
Brand
GLPBIO
Computed properties PubChem CID 21192822 · TPSA 107 Ų · H-bond donors 3 · H-bond acceptors 7
TPSA
107 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
1
Heavy atoms
29

SMILES C1CN(CCC12NC3=C(C=CC(=C3C(=N2)N)F)F)C(=O)C4=CN=C(C=C4)C#N.Cl

Computed descriptors from PubChem (CID 21192822), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.