Loading...
Chemical structure of Vat-Cit-PAB-Monomethyl Dolastatin 10

GC38480

Vat-Cit-PAB-Monomethyl Dolastatin 10

Also known as [4-[[(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]phenyl]methyl N-[(2S)-1-[[(2S)-1-[[(3R,4S,5S)-3-methoxy-1-[(2R)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino]propyl]pyrrolidin-1-yl]-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-N-methylcarbamate

Vat-Cit-PAB-Monomethyl Dolastatin 10 is a drug-linker conjugate for ADC with potent antitumor activity by using Monomethyl Dolastatin 10 (a potent tubulin inhibitor), linked via the ADC linker Vat-Cit-PAB

ChemicalCAS1415329-13-3MW1176.51FormulaC60H93N11O11S
CAS number
1415329-13-3
Molecular weight
1176.51
Formula
C60H93N11O11S
Solubility
Soluble in DMSO
InChIKey
GXCUHADNABTLIA-DBHCVZOLSA-N
Catalogue number
GC38480
Brand
GLPBIO
Computed properties PubChem CID 129896992 · XLogP 5.6 · TPSA 327 Ų · H-bond donors 7
XLogP
5.6
TPSA
327 Ų
H-bond donors
7
H-bond acceptors
14
Rotatable bonds
33
Heavy atoms
83

SMILES CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@@H]1[C@@H]([C@@H](C)C(=O)N[C@@H](CC2=CC=CC=C2)C3=NC=CS3)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)OCC4=CC=C(C=C4)NC(=O)[C@H](CCCNC(=O)N)NC(=O)[C@H](C(C)C)N

Computed descriptors from PubChem (CID 129896992), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.