Loading...
Chemical structure of Remibrutinib

GC38375

Remibrutinib

Also known as N-[3-[6-amino-5-[2-[methyl(prop-2-enoyl)amino]ethoxy]pyrimidin-4-yl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluorobenzamide

Remibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM

ChemicalCAS1787294-07-8MW507.53FormulaC27H27F2N5O3
CAS number
1787294-07-8
Molecular weight
507.53
Formula
C27H27F2N5O3
Solubility
DMSO： 125 mg/mL (246·29 mM)
InChIKey
CUABMPOJOBCXJI-UHFFFAOYSA-N
Catalogue number
GC38375
Brand
GLPBIO
Computed properties PubChem CID 118107483 · XLogP 3.9 · TPSA 110 Ų · H-bond donors 2
XLogP
3.9
TPSA
110 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
9
Heavy atoms
37

SMILES CC1=C(C=C(C=C1NC(=O)C2=C(C=C(C=C2)C3CC3)F)F)C4=C(C(=NC=N4)N)OCCN(C)C(=O)C=C

Computed descriptors from PubChem (CID 118107483), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.