GC38350
Epertinib hydrochloride
Also known as N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[(Z)-N-[[(3R)-morpholin-3-yl]methoxy]-C-prop-1-ynylcarbonimidoyl]quinazolin-4-amine;hydrochloride
Epertinib hydrochloride (S-22611 hydrochloride) is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1·48 nM, 7·15 nM and 2·49 nM, respectively· Epertinib hydrochloride shows potent antitumor activity
ChemicalCAS2071195-74-7MW596.48FormulaC30H28Cl2FN5O3
- CAS number
- 2071195-74-7
- Molecular weight
- 596.48
- Formula
- C30H28Cl2FN5O3
- Solubility
- DMSO： 125 mg/mL (209·56 mM)
- InChIKey
- NVWJPQQXBPWOOA-PLXRJBJVSA-N
- Catalogue number
- GC38350
- Brand
- GLPBIO
Computed properties PubChem CID 139290994 · TPSA 89.9 Ų · H-bond donors 3 · H-bond acceptors 9
- TPSA
- 89.9 Ų
- H-bond donors
- 3
- H-bond acceptors
- 9
- Rotatable bonds
- 10
- Heavy atoms
- 41
SMILES CC#C/C(=N\OC[C@H]1COCCN1)/C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl.Cl
Computed descriptors from PubChem (CID 139290994), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il