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Chemical structure of DNA2 inhibitor C5

GC38207

DNA2 inhibitor C5

Also known as 8-nitro-4-oxo-1H-quinoline-3-carboxylic acid

DNA2 inhibitor C5 is a potent, competitive and specific inhibitor of DNA2 nuclease activity with an IC50 of 20 μM· DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2· DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress

ChemicalCAS35973-25-2MW234.17FormulaC10H6N2O5
CAS number
35973-25-2
Molecular weight
234.17
Formula
C10H6N2O5
Solubility
DMSO： 31·25 mg/mL (133·45 mM)
InChIKey
BMIZBCVEHSUUNO-UHFFFAOYSA-N
Catalogue number
GC38207
Brand
GLPBIO
Computed properties PubChem CID 225906 · XLogP 1.7 · TPSA 112 Ų · H-bond donors 2
XLogP
1.7
TPSA
112 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
1
Heavy atoms
17

SMILES C1=CC2=C(C(=C1)[N+](=O)[O-])NC=C(C2=O)C(=O)O

Computed descriptors from PubChem (CID 225906), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.