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Chemical structure of ML753286

GC38129

ML753286

Also known as (2S,5S,8R)-14-methoxy-5-methyl-2-(2-methylpropyl)-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione

ML753286 is an orally active and selective BCRP (Breast cancer resistance protein) inhibitor with an IC50 of 0·6 μM· ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions, and is stable in plasma cross species

ChemicalCAS1699720-89-2MW355.43FormulaC20H25N3O3
CAS number
1699720-89-2
Molecular weight
355.43
Formula
C20H25N3O3
Solubility
Soluble in DMSO
InChIKey
XDVXQQDQFWVCAU-MZPVMMEZSA-N
Catalogue number
GC38129
Brand
GLPBIO
Computed properties PubChem CID 118017423 · XLogP 2.7 · TPSA 74.4 Ų · H-bond donors 2
XLogP
2.7
TPSA
74.4 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
3
Heavy atoms
26

SMILES C[C@H]1C(=O)N2[C@H](CC3=C([C@@H]2CC(C)C)NC4=C3C=CC(=C4)OC)C(=O)N1

Computed descriptors from PubChem (CID 118017423), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.