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Chemical structure of Handelin

GC38025

Handelin

Also known as [(2'R,5R,6S,9'S,9bS)-2',6-dihydroxy-2',6,9,11'-tetramethyl-6'-methylidene-2,7'-dioxospiro[4,5,6a,7,9a,9b-hexahydro-3aH-azuleno[4,5-b]furan-3,15'-8-oxatetracyclo[9.2.2.01,10.05,9]pentadec-12-ene]-5-yl] acetate

Handelin is a guaianolide dimer from Chrysanthemum boreale that has potent anti-inflammatory activity by down-regulating NF-κB signaling and pro-inflammatory cytokine production

ChemicalCAS62687-22-3MW552.66FormulaC32H40O8
CAS number
62687-22-3
Molecular weight
552.66
Formula
C32H40O8
Solubility
DMSO ： 16·67 mg/mL (30·16 mM; Need ultrasonic)
InChIKey
DSNIKOZTDZBWKD-XMNJDQQWSA-N
Catalogue number
GC38025
Brand
GLPBIO
Computed properties PubChem CID 3085251 · XLogP 2.9 · TPSA 119 Ų · H-bond donors 2
XLogP
2.9
TPSA
119 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
2
Heavy atoms
40

SMILES CC1=CCC2C1[C@@H]3C(C[C@H]([C@@]2(C)O)OC(=O)C)C4(CC56C=CC4(C5[C@@H]7C(CC[C@@]6(C)O)C(=C)C(=O)O7)C)C(=O)O3

Computed descriptors from PubChem (CID 3085251), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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