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Chemical structure of SPDB-sulfo

GC38017

SPDB-sulfo

Also known as 2,5-dioxo-1-[4-(pyridin-2-yldisulfanyl)butanoyloxy]pyrrolidine-3-sulfonic acid

SPDB-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs)

ChemicalCAS1628113-16-5MW406.45FormulaC13H14N2O7S3
CAS number
1628113-16-5
Molecular weight
406.45
Formula
C13H14N2O7S3
Solubility
Soluble in DMSO
InChIKey
QTOCZEQWVKQCHD-UHFFFAOYSA-N
Catalogue number
GC38017
Brand
GLPBIO
Computed properties PubChem CID 90417461 · XLogP 0.6 · TPSA 190 Ų · H-bond donors 1
XLogP
0.6
TPSA
190 Ų
H-bond donors
1
H-bond acceptors
10
Rotatable bonds
9
Heavy atoms
25

SMILES C1C(C(=O)N(C1=O)OC(=O)CCCSSC2=CC=CC=N2)S(=O)(=O)O

Computed descriptors from PubChem (CID 90417461), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
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