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Chemical structure of β-Hydroxyisovalerylshikonin

GC38006

β-Hydroxyisovalerylshikonin

Also known as [1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] 3-hydroxy-3-methylbutanoate

Beta-hydroxyisovalerylshikonin is a natural product isolated from Lithospermium radix, acts as a potent inhibitor of protein tyrosine kinases (PTK), with IC50s of 0·7μM and 1μM for EGFR and v-Src receptor, respectively· Beta-hydroxyisovalerylshikonin is effective against a wide variety of tumor cell lines, and most efficiently induces cell-death in NCI-H522 and DMS114 cells

ChemicalCAS7415-78-3MW388.41FormulaC21H24O7
CAS number
7415-78-3
Molecular weight
388.41
Formula
C21H24O7
Solubility
Soluble in DMSO
InChIKey
MXANJRGHSFELEJ-UHFFFAOYSA-N
Catalogue number
GC38006
Brand
GLPBIO
Computed properties PubChem CID 100203 · XLogP 3.4 · TPSA 121 Ų · H-bond donors 3
XLogP
3.4
TPSA
121 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
28

SMILES CC(=CCC(C1=CC(=O)C2=C(C=CC(=C2C1=O)O)O)OC(=O)CC(C)(C)O)C

Computed descriptors from PubChem (CID 100203), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.