GC37857
UNC2025 hydrochloride
Also known as 4-[2-(butylamino)-5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexan-1-ol;hydrochloride
UNC2025 hydrochloride is a potent, ATP-competitive, and highly orally active Mer/Flt3 inhibitor with IC50 values of 0·74 nM and 0·8 nM, respectively· UNC2025 hydrochloride is >45-fold selectivity for MERTK relative to Axl (IC50= 122 nM; Ki?= 13·3 nM)· UNC2025 hydrochloride exhibits an excellent PK properties, and can be used for the investigation of acute leukemia
ChemicalCAS2070015-17-5MW513.12FormulaC28H41ClN6O
- CAS number
- 2070015-17-5
- Molecular weight
- 513.12
- Formula
- C28H41ClN6O
- Solubility
- DMSO： 6·66 mg/mL (12·98 mM)
- InChIKey
- NYHAEAZNSGIAPV-UHFFFAOYSA-N
- Catalogue number
- GC37857
- Brand
- GLPBIO
Computed properties PubChem CID 92044362 · TPSA 69.5 Ų · H-bond donors 3 · H-bond acceptors 6
- TPSA
- 69.5 Ų
- H-bond donors
- 3
- H-bond acceptors
- 6
- Rotatable bonds
- 8
- Heavy atoms
- 36
SMILES CCCCNC1=NC=C2C(=CN(C2=N1)C3CCC(CC3)O)C4=CC=C(C=C4)CN5CCN(CC5)C.Cl
Computed descriptors from PubChem (CID 92044362), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il