GC37808
Toceranib phosphate
Also known as 5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-(2-pyrrolidin-1-ylethyl)-1H-pyrrole-3-carboxamide;phosphoric acid
Toceranib phosphate (SU11654 phosphate) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR, VEGFR, and Kit with Kis of 5 and 6 nM for PDGFRβ and Flk-1/KDR, respectively· Toceranib phosphate (SU11654 phosphate) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors
ChemicalCAS874819-74-6MW494.45FormulaC22H28FN4O6P
- CAS number
- 874819-74-6
- Molecular weight
- 494.45
- Formula
- C22H28FN4O6P
- Solubility
- DMSO： 2·46 mg/mL (4·98 mM and warming); Water： ＜ 0·1 mg/mL (insoluble)
- InChIKey
- AOORBROPMMRREB-HBPAQXCTSA-N
- Catalogue number
- GC37808
- Brand
- GLPBIO
Computed properties PubChem CID 16034840 · TPSA 155 Ų · H-bond donors 6 · H-bond acceptors 8
- TPSA
- 155 Ų
- H-bond donors
- 6
- H-bond acceptors
- 8
- Rotatable bonds
- 5
- Heavy atoms
- 34
SMILES CC1=C(NC(=C1C(=O)NCCN2CCCC2)C)/C=C\3/C4=C(C=CC(=C4)F)NC3=O.OP(=O)(O)O
Computed descriptors from PubChem (CID 16034840), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il