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Chemical structure of TG 100572

GC37771

TG 100572

Also known as 4-chloro-3-[5-methyl-3-[4-(2-pyrrolidin-1-ylethoxy)anilino]-1,2,4-benzotriazin-7-yl]phenol

TG 100572 is a multi-targeted kinase inhibitor which inhibits receptor tyrosine kinases and Src kinases; has IC50s of 2, 7, 2, 16, 13, 5, 0·5, 6, 0·1, 0·4, 1, 0·2 nM for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively

ChemicalCAS867334-05-2MW475.97FormulaC26H26ClN5O2
CAS number
867334-05-2
Molecular weight
475.97
Formula
C26H26ClN5O2
Solubility
DMSO： ≥ 150 mg/mL (315·15 mM)
InChIKey
AQSSMEORRLJZLU-UHFFFAOYSA-N
Catalogue number
GC37771
Brand
GLPBIO
Computed properties PubChem CID 11712625 · XLogP 5.3 · TPSA 83.4 Ų · H-bond donors 2
XLogP
5.3
TPSA
83.4 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
34

SMILES CC1=CC(=CC2=C1N=C(N=N2)NC3=CC=C(C=C3)OCCN4CCCC4)C5=C(C=CC(=C5)O)Cl

Computed descriptors from PubChem (CID 11712625), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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