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Chemical structure of Tefinostat

GC37753

Tefinostat

Also known as cyclopentyl (2S)-2-[[4-[[8-(hydroxyamino)-8-oxooctanoyl]amino]phenyl]methylamino]-2-phenylacetate

Tefinostat (CHR-2845) is a monocyte/macrophage targeted histone deacetylase (HDAC) inhibitor· Tefinostat can be cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1)· Tefinostat can be used for the research of leukaemias

ChemicalCAS914382-60-8MW495.61FormulaC28H37N3O5
CAS number
914382-60-8
Molecular weight
495.61
Formula
C28H37N3O5
Solubility
DMSO： 100 mg/mL (201·77 mM)
InChIKey
GLNWREBYRLDPQP-MHZLTWQESA-N
Catalogue number
GC37753
Brand
GLPBIO
Computed properties PubChem CID 15940949 · XLogP 3.8 · TPSA 117 Ų · H-bond donors 4
XLogP
3.8
TPSA
117 Ų
H-bond donors
4
H-bond acceptors
6
Rotatable bonds
15
Heavy atoms
36

SMILES C1CCC(C1)OC(=O)[C@H](C2=CC=CC=C2)NCC3=CC=C(C=C3)NC(=O)CCCCCCC(=O)NO

Computed descriptors from PubChem (CID 15940949), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.