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Chemical structure of SSR128129E free acid

GC37679

SSR128129E free acid

Also known as 2-amino-5-(1-methoxy-2-methylindolizine-3-carbonyl)benzoic acid

SSR128129E free acid is an orally available and allosteric FGFR inhibitor with an IC50 of 1·9 μM for FGFR1

ChemicalCAS848463-13-8MW324.33FormulaC18H16N2O4
CAS number
848463-13-8
Molecular weight
324.33
Formula
C18H16N2O4
Solubility
Soluble in DMSO
InChIKey
SNMCWIDCSPHZRD-UHFFFAOYSA-N
Catalogue number
GC37679
Brand
GLPBIO
Computed properties PubChem CID 11347895 · XLogP 3.9 · TPSA 94 Ų · H-bond donors 2
XLogP
3.9
TPSA
94 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
24

SMILES CC1=C(N2C=CC=CC2=C1OC)C(=O)C3=CC(=C(C=C3)N)C(=O)O

Computed descriptors from PubChem (CID 11347895), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
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