Loading...
Chemical structure of Seviteronel

GC37631

Seviteronel

Also known as (1S)-1-[6,7-bis(difluoromethoxy)naphthalen-2-yl]-2-methyl-1-(2H-triazol-4-yl)propan-1-ol

Seviteronel (VT-464) is a potent CYP17 lyase inhibitor(h-Lyase IC50=69 nM) that demonstrated both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral activity in a hamster model of androgen biosynthesis inhibition

ChemicalCAS1610537-15-9MW399.34FormulaC18H17F4N3O3
CAS number
1610537-15-9
Molecular weight
399.34
Formula
C18H17F4N3O3
Solubility
DMSO： ≥ 50 mg/mL (125·21 mM)
InChIKey
ZBRAJOQFSNYJMF-SFHVURJKSA-N
Catalogue number
GC37631
Brand
GLPBIO
Computed properties PubChem CID 78357816 · XLogP 4.7 · TPSA 80.3 Ų · H-bond donors 2
XLogP
4.7
TPSA
80.3 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
7
Heavy atoms
28

SMILES CC(C)[C@](C1=CC2=CC(=C(C=C2C=C1)OC(F)F)OC(F)F)(C3=NNN=C3)O

Computed descriptors from PubChem (CID 78357816), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.