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Chemical structure of SB269652

GC37598

SB269652

Also known as N-[4-[2-(7-cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclohexyl]-1H-indole-2-carboxamide

SB269652 is the first drug-like allosteric modulator of the dopamine D2 receptor (D2R); a new chemical probe that can differentiate D2R monomers from dimers or oligomers depending on the observed pharmacology

ChemicalCAS215802-15-6MW426.55FormulaC27H30N4O
CAS number
215802-15-6
Molecular weight
426.55
Formula
C27H30N4O
Solubility
DMSO ： 2 mg/mL (4·69 mM; Need ultrasonic and warming)
InChIKey
JGLGOAQPUQITLD-UHFFFAOYSA-N
Catalogue number
GC37598
Brand
GLPBIO
Computed properties PubChem CID 9910352 · XLogP 4.8 · TPSA 71.9 Ų · H-bond donors 2
XLogP
4.8
TPSA
71.9 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
5
Heavy atoms
32

SMILES C1CC(CCC1CCN2CCC3=C(C2)C=C(C=C3)C#N)NC(=O)C4=CC5=CC=CC=C5N4

Computed descriptors from PubChem (CID 9910352), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.