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Chemical structure of SB 242235

GC37595

SB 242235

Also known as 4-[5-(4-fluorophenyl)-3-piperidin-4-ylimidazol-4-yl]-2-methoxypyrimidine

SB-242235 is a potent and selective p38 MAP kinase inhibitor, with an IC50 of 1·0 μM in primary human chondrocytes

ChemicalCAS193746-75-7MW353.39FormulaC19H20FN5O
CAS number
193746-75-7
Molecular weight
353.39
Formula
C19H20FN5O
Solubility
DMSO: ≥ 48 mg/mL (135·83 mM)
InChIKey
PDTYLGXVBIWRIM-UHFFFAOYSA-N
Catalogue number
GC37595
Brand
GLPBIO
Computed properties PubChem CID 9863367 · XLogP 2.1 · TPSA 64.9 Ų · H-bond donors 1
XLogP
2.1
TPSA
64.9 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
26

SMILES COC1=NC=CC(=N1)C2=C(N=CN2C3CCNCC3)C4=CC=C(C=C4)F

Computed descriptors from PubChem (CID 9863367), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.