GC37580
SAG hydrochloride
Also known as 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide;hydrochloride
SAG hydrochloride is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM)· SAG hydrochloride activates the Hedgehog signaling pathway and counteracts Cyclopamine inhibition of Smo
ChemicalCAS2095432-58-7MW526.52FormulaC28H29Cl2N3OS
- CAS number
- 2095432-58-7
- Molecular weight
- 526.52
- Formula
- C28H29Cl2N3OS
- Solubility
- H2O ： 25 mg/mL (47·48 mM; Need ultrasonic); DMSO ： 21·67 mg/mL (41·16 mM; Need ultrasonic)
- InChIKey
- CRWTYWYPPITOOZ-UHFFFAOYSA-N
- Catalogue number
- GC37580
- Brand
- GLPBIO
Computed properties PubChem CID 121540649 · TPSA 73.5 Ų · H-bond donors 2 · H-bond acceptors 4
- TPSA
- 73.5 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Rotatable bonds
- 6
- Heavy atoms
- 35
SMILES CNC1CCC(CC1)N(CC2=CC(=CC=C2)C3=CC=NC=C3)C(=O)C4=C(C5=CC=CC=C5S4)Cl.Cl
Computed descriptors from PubChem (CID 121540649), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il