Loading...
Chemical structure of RU-SKI 43

GC37573

RU-SKI 43

Also known as 2-(2-methylbutylamino)-1-[4-[(3-methylphenoxy)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl]ethanone

RU-SKI 43 is a potent and selective Hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM· RU-SKI 43 reduces Gli-1 activation through Smoothened-independent non-canonical signaling and decreases Akt and mTOR pathway activity· RU-SKI 43 has anti-cancer activity

ChemicalCAS1043797-53-0MW386.55FormulaC22H30N2O2S
CAS number
1043797-53-0
Molecular weight
386.55
Formula
C22H30N2O2S
Solubility
Soluble in DMSO
InChIKey
AEENEMOEBJOKGN-UHFFFAOYSA-N
Catalogue number
GC37573
Brand
GLPBIO
Computed properties PubChem CID 46006640 · XLogP 4.3 · TPSA 69.8 Ų · H-bond donors 1
XLogP
4.3
TPSA
69.8 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
8
Heavy atoms
27

SMILES CCC(C)CNCC(=O)N1CCC2=C(C1COC3=CC=CC(=C3)C)C=CS2

Computed descriptors from PubChem (CID 46006640), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.