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Chemical structure of RU 24969

GC37569

RU 24969

Also known as 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

RU 24969 is a preferential 5-HT1B agonist, with a Ki of 0·38 nM, but also displays appreciable affinity for the 5-HT1A receptor (Ki=2·5 nM), and has low affinity for other receptor sites in the brain

ChemicalCAS66611-26-5MW228.29FormulaC14H16N2O
CAS number
66611-26-5
Molecular weight
228.29
Formula
C14H16N2O
Solubility
DMSO: ≥ 30 mg/mL (131·41 mM)
InChIKey
KRVMLPUDAOWOGN-UHFFFAOYSA-N
Catalogue number
GC37569
Brand
GLPBIO
Computed properties PubChem CID 108029 · XLogP 1.8 · TPSA 37.1 Ų · H-bond donors 2
XLogP
1.8
TPSA
37.1 Ų
H-bond donors
2
H-bond acceptors
2
Rotatable bonds
2
Heavy atoms
17

SMILES COC1=CC2=C(C=C1)NC=C2C3=CCNCC3

Computed descriptors from PubChem (CID 108029), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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