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Chemical structure of Ravoxertinib hydrochloride

GC37071

Ravoxertinib hydrochloride

Also known as 1-[(1S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one;hydrochloride

Ravoxertinib hydrochloride (GDC-0994 hydrochloride) is an orally bioavailable inhibitor selective for ERK kinase activity with IC50 of 6·1 nM and 3·1 nM for ERK1 and ERK2, respectively

ChemicalCAS2070009-58-2MW477.32FormulaC21H19Cl2FN6O2
CAS number
2070009-58-2
Molecular weight
477.32
Formula
C21H19Cl2FN6O2
Solubility
DMSO： 100 mg/mL (209·50 mM)
InChIKey
RMNVBUVHPAETTJ-GMUIIQOCSA-N
Catalogue number
GC37071
Brand
GLPBIO
Computed properties PubChem CID 92044395 · TPSA 96.2 Ų · H-bond donors 3 · H-bond acceptors 7
TPSA
96.2 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
32

SMILES CN1C(=CC=N1)NC2=NC=CC(=N2)C3=CC(=O)N(C=C3)[C@H](CO)C4=CC(=C(C=C4)Cl)F.Cl

Computed descriptors from PubChem (CID 92044395), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.