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Chemical structure of Pyrazofurin

GC37042

Pyrazofurin

Also known as 3-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1H-pyrazole-5-carboxamide

Pyrazofurin, a pyrimidine nucleoside analogue with antineoplastic activity, inhibits cell proliferation and DNA synthesis in cells by inhibiting uridine 5'-phosphate (UMP) synthase· Pyrazofurin is an active, sensitive orotate-phosphoribosyltransferase inhibitor with IC50s between 0·06-0·37 ?M in the three squamous cell carcinoma (SCC) cell lines Hep-2, HNSCC-14B and HNSCC-14C

ChemicalCAS30868-30-5MW259.22FormulaC9H13N3O6
CAS number
30868-30-5
Molecular weight
259.22
Formula
C9H13N3O6
Solubility
Soluble in DMSO
InChIKey
XESARGFCSKSFID-FLLFQEBCSA-N
Catalogue number
GC37042
Brand
GLPBIO
Computed properties PubChem CID 135413551 · XLogP -2.2 · TPSA 162 Ų · H-bond donors 6
XLogP
-2.2
TPSA
162 Ų
H-bond donors
6
H-bond acceptors
7
Rotatable bonds
3
Heavy atoms
18

SMILES C([C@@H]1[C@H]([C@H]([C@@H](O1)C2=NNC(=C2O)C(=O)N)O)O)O

Computed descriptors from PubChem (CID 135413551), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.