Loading...
Chemical structure of PFE-360

GC36888

PFE-360

Also known as 1-methyl-4-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrrole-2-carbonitrile

PFE-360 (PF-06685360) is a potent, selective, brain penetrated and orally active leucine-rich repeat kinase 2 (LRRK2) inhibitor with a mean IC50 of 2·3 nM in vivo

ChemicalCAS1527475-61-1MW308.34FormulaC16H16N6O
CAS number
1527475-61-1
Molecular weight
308.34
Formula
C16H16N6O
Solubility
DMSO： 10·42 mg/mL (33·79 mM)
InChIKey
IYQTYHISVSPMSU-UHFFFAOYSA-N
Catalogue number
GC36888
Brand
GLPBIO
Computed properties PubChem CID 89915073 · XLogP 1.2 · TPSA 82.8 Ų · H-bond donors 1
XLogP
1.2
TPSA
82.8 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
23

SMILES CN1C=C(C=C1C#N)C2=CNC3=C2C(=NC=N3)N4CCOCC4

Computed descriptors from PubChem (CID 89915073), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.