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Chemical structure of OSU-T315

GC36821

OSU-T315

Also known as N-methyl-3-[1-(4-piperazin-1-ylphenyl)-3-[4-[4-(trifluoromethyl)phenyl]phenyl]pyrazol-5-yl]propanamide

OSU-T315 (ILK-IN-1) is a small Integrin-linked kinase (ILK) inhibitor with an IC50 of 0·6 μM, inhibiting PI3K/AKT signaling by dephosphorylation of AKT-Ser473 and other ILK targets (GSK-3β and myosin light chain)· OSU-T315 abrogates AKT activation by impeding AKT localization in lipid rafts and triggers caspase-dependent apoptosis in an ILK-independent manner· OSU-T315 causes cell death through apoptosis and autophagy

ChemicalCAS2070015-22-2MW533.59FormulaC30H30F3N5O
CAS number
2070015-22-2
Molecular weight
533.59
Formula
C30H30F3N5O
Solubility
DMSO： ≥ 50 mg/mL (93·70 mM); Water： ＜ 0·1 mg/mL (insoluble)
InChIKey
AJLOJUFSIDSBNN-UHFFFAOYSA-N
Catalogue number
GC36821
Brand
GLPBIO
Computed properties PubChem CID 118986645 · XLogP 5.1 · TPSA 62.2 Ų · H-bond donors 2
XLogP
5.1
TPSA
62.2 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
39

SMILES CNC(=O)CCC1=CC(=NN1C2=CC=C(C=C2)N3CCNCC3)C4=CC=C(C=C4)C5=CC=C(C=C5)C(F)(F)F

Computed descriptors from PubChem (CID 118986645), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.