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Chemical structure of NNC-0640

GC36753

NNC-0640

Also known as 4-[[4-cyclohexyl-N-[(3-methylsulfonylphenyl)carbamoyl]anilino]methyl]-N-(2H-tetrazol-5-yl)benzamide

NNC-0640 is a potent human G-protein-coupled glucagon receptor (GCGR) negative allosteric modulator (NAM) with an IC50 of 69·2 nM

ChemicalCAS307986-98-7MW573.67FormulaC29H31N7O4S
CAS number
307986-98-7
Molecular weight
573.67
Formula
C29H31N7O4S
Solubility
DMSO: 250 mg/mL (435·79 mM)
InChIKey
PPTKULJUDJWTSA-UHFFFAOYSA-N
Catalogue number
GC36753
Brand
GLPBIO
Computed properties PubChem CID 23549991 · XLogP 4.7 · TPSA 158 Ų · H-bond donors 3
XLogP
4.7
TPSA
158 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
8
Heavy atoms
41

SMILES CS(=O)(=O)C1=CC=CC(=C1)NC(=O)N(CC2=CC=C(C=C2)C(=O)NC3=NNN=N3)C4=CC=C(C=C4)C5CCCCC5

Computed descriptors from PubChem (CID 23549991), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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