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Chemical structure of NG 52

GC36732

NG 52

Also known as 2-[[6-(3-chloroanilino)-9-propan-2-ylpurin-2-yl]amino]ethanol

NG 52 is a potent, cell-permeable, selective, ATP-compatible and orally active Cdc28p and Pho85p kinase inhibitor with IC50s of 7 μM and 2 μM, respectively· NG 52 also inhibits the activity of phosphoglycerate kinase 1 (PGK1) with an IC50 of 2·5 μM· NG 52 is inactive against yeast kinases Kin28p, Srb10, and Cak1p

ChemicalCAS212779-48-1MW346.81FormulaC16H19ClN6O
CAS number
212779-48-1
Molecular weight
346.81
Formula
C16H19ClN6O
Solubility
DMSO： 100 mg/mL (288·34 mM)
InChIKey
XZEFMZCNXDQXOZ-UHFFFAOYSA-N
Catalogue number
GC36732
Brand
GLPBIO
Computed properties PubChem CID 2856 · XLogP 2.9 · TPSA 87.9 Ų · H-bond donors 3
XLogP
2.9
TPSA
87.9 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
24

SMILES CC(C)N1C=NC2=C(N=C(N=C21)NCCO)NC3=CC(=CC=C3)Cl

Computed descriptors from PubChem (CID 2856), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.