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Chemical structure of Minodronic acid

GC36613

Minodronic acid

Also known as (1-hydroxy-2-imidazo[1,2-a]pyridin-3-yl-1-phosphonoethyl)phosphonic acid

Minodronic acid (YM-529) is a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis, and inhibits metastasis of various types of cancer cells· Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors involved in pain

ChemicalCAS180064-38-4MW322.15FormulaC9H12N2O7P2
CAS number
180064-38-4
Molecular weight
322.15
Formula
C9H12N2O7P2
Solubility
Water: 5 mg/mL (15·52 mM and warming); DMSO: < 1 mg/mL (insoluble or slightly soluble)
InChIKey
VMMKGHQPQIEGSQ-UHFFFAOYSA-N
Catalogue number
GC36613
Brand
GLPBIO
Computed properties PubChem CID 130956 · XLogP -2.2 · TPSA 153 Ų · H-bond donors 5
XLogP
-2.2
TPSA
153 Ų
H-bond donors
5
H-bond acceptors
8
Rotatable bonds
4
Heavy atoms
20

SMILES C1=CC2=NC=C(N2C=C1)CC(O)(P(=O)(O)O)P(=O)(O)O

Computed descriptors from PubChem (CID 130956), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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