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Chemical structure of MF-438

GC36604

MF-438

Also known as 2-methyl-5-[6-[4-[2-(trifluoromethyl)phenoxy]piperidin-1-yl]pyridazin-3-yl]-1,3,4-thiadiazole

MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an IC50 of 2·3 nM for rSCD1

ChemicalCAS921605-87-0MW421.44FormulaC19H18F3N5OS
CAS number
921605-87-0
Molecular weight
421.44
Formula
C19H18F3N5OS
Solubility
DMSO： 62·5 mg/mL (148·30 mM)
InChIKey
NVUJDKDVOZVALT-UHFFFAOYSA-N
Catalogue number
GC36604
Brand
GLPBIO
Computed properties PubChem CID 16042458 · XLogP 3.9 · TPSA 92.3 Ų · H-bond donors 0
XLogP
3.9
TPSA
92.3 Ų
H-bond donors
0
H-bond acceptors
10
Rotatable bonds
4
Heavy atoms
29

SMILES CC1=NN=C(S1)C2=NN=C(C=C2)N3CCC(CC3)OC4=CC=CC=C4C(F)(F)F

Computed descriptors from PubChem (CID 16042458), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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