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Chemical structure of LY2922470

GC36507

LY2922470

Also known as (3S)-3-[4-[[5-[(8-methoxy-3,4-dihydro-2H-quinolin-1-yl)methyl]thiophen-2-yl]methoxy]phenyl]hex-4-ynoic acid

LY2922470 is a potent, selective and orally available agonist of the G protein-coupled receptor 40 (GPR40), with EC50s of 7 nM, 1 nM and 3 nM for human GPR40, mouse GPR40 and rat GPR40, respectively

ChemicalCAS1423018-12-5MW475.6FormulaC28H29NO4S
CAS number
1423018-12-5
Molecular weight
475.6
Formula
C28H29NO4S
Solubility
DMSO： ≥ 125 mg/mL (262·83 mM)
InChIKey
VJVDLRVFJTVWEO-QFIPXVFZSA-N
Catalogue number
GC36507
Brand
GLPBIO
Computed properties PubChem CID 71257551 · XLogP 5.5 · TPSA 87.2 Ų · H-bond donors 1
XLogP
5.5
TPSA
87.2 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
9
Heavy atoms
34

SMILES CC#C[C@@H](CC(=O)O)C1=CC=C(C=C1)OCC2=CC=C(S2)CN3CCCC4=C3C(=CC=C4)OC

Computed descriptors from PubChem (CID 71257551), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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