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Chemical structure of Lucidenic acid B

GC36488

Lucidenic acid B

Also known as 4-(7,12-dihydroxy-4,4,10,13,14-pentamethyl-3,11,15-trioxo-1,2,5,6,7,12,16,17-octahydrocyclopenta[a]phenanthren-17-yl)pentanoic acid

Lucidenic acid B is a natural compound isolated from Ganoderma lucidum, induces apoptosis of cancer cells, and causes the activation of caspase-9 and caspase-3, and cleavage of PARP· Lucidenic acid B does not affect the cell cycle profile, or the number of necrotic cells

ChemicalCAS95311-95-8MW474.59FormulaC27H38O7
CAS number
95311-95-8
Molecular weight
474.59
Formula
C27H38O7
Solubility
Soluble in DMSO
InChIKey
GYRDSOABOBCYST-UHFFFAOYSA-N
Catalogue number
GC36488
Brand
GLPBIO
Computed properties PubChem CID 14109380 · XLogP 1.5 · TPSA 129 Ų · H-bond donors 3
XLogP
1.5
TPSA
129 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
34

SMILES CC(CCC(=O)O)C1CC(=O)C2(C1(C(C(=O)C3=C2C(CC4C3(CCC(=O)C4(C)C)C)O)O)C)C

Computed descriptors from PubChem (CID 14109380), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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