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Chemical structure of Licochalcone E

GC36447

Licochalcone E

Also known as (E)-3-[4-hydroxy-2-methoxy-5-[(2S)-3-methylbut-3-en-2-yl]phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one

Licochalcone E, a flavonoid compound isolated from Glycyrrhiza inflate, inhibits NF-κB and AP-1 transcriptional activity through the inhibition of AKT and MAPK activation

ChemicalCAS864232-34-8MW338.4FormulaC21H22O4
CAS number
864232-34-8
Molecular weight
338.4
Formula
C21H22O4
Solubility
DMSO: 125 mg/mL (369·39 mM)
InChIKey
SWPKMTGYQGHLJS-RNVIBTMRSA-N
Catalogue number
GC36447
Brand
GLPBIO
Computed properties PubChem CID 46209991 · XLogP 5 · TPSA 66.8 Ų · H-bond donors 2
XLogP
5
TPSA
66.8 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
6
Heavy atoms
25

SMILES C[C@H](C1=C(C=C(C(=C1)/C=C/C(=O)C2=CC=C(C=C2)O)OC)O)C(=C)C

Computed descriptors from PubChem (CID 46209991), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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Documents
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