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Chemical structure of Lesinurad sodium

GC36439

Lesinurad sodium

Also known as sodium 2-[[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-1,2,4-triazol-3-yl]sulfanyl]acetate

Lesinurad sodium is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0·85 and 2 ?M, respectively

ChemicalCAS1151516-14-1MW426.26FormulaC17H13BrN3NaO2S
CAS number
1151516-14-1
Molecular weight
426.26
Formula
C17H13BrN3NaO2S
Solubility
DMSO: ≥ 26 mg/mL (61·00 mM)
InChIKey
FVYMVLTWIBGEMC-UHFFFAOYSA-M
Catalogue number
GC36439
Brand
GLPBIO
Computed properties PubChem CID 56928182 · TPSA 96.1 Ų · H-bond donors 0 · H-bond acceptors 5
TPSA
96.1 Ų
H-bond donors
0
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
25

SMILES C1CC1C2=CC=C(C3=CC=CC=C23)N4C(=NN=C4Br)SCC(=O)[O-].[Na+]

Computed descriptors from PubChem (CID 56928182), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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