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Chemical structure of Keap1-Nrf2-IN-1

GC36390

Keap1-Nrf2-IN-1

Also known as (2S)-1-[4-[carboxymethyl-(4-methoxyphenyl)sulfonylamino]naphthalen-1-yl]pyrrolidine-2-carboxylic acid

Keap1-Nrf2-IN-1 is a Keap1 (Kelch-like ECH-associated protein 1)-Nrf2 (nuclear factor erythroid 2-related factor 2) protein-protein interaction inhibitor, and with an IC50 of 43 nM for Keap1 protein

ChemicalCAS2232112-72-8MW484.52FormulaC24H24N2O7S
CAS number
2232112-72-8
Molecular weight
484.52
Formula
C24H24N2O7S
Solubility
Soluble in DMSO
InChIKey
XIIZECUWKNXLCU-QFIPXVFZSA-N
Catalogue number
GC36390
Brand
GLPBIO
Computed properties PubChem CID 138911332 · XLogP 3.7 · TPSA 133 Ų · H-bond donors 2
XLogP
3.7
TPSA
133 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
8
Heavy atoms
34

SMILES COC1=CC=C(C=C1)S(=O)(=O)N(CC(=O)O)C2=CC=C(C3=CC=CC=C32)N4CCC[C@H]4C(=O)O

Computed descriptors from PubChem (CID 138911332), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.