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Chemical structure of KAN0438757

GC36383

KAN0438757

Also known as 2-hydroxyethyl 4-[[3-(5-fluoro-2-hydroxyphenyl)phenyl]sulfonylamino]-2-hydroxybenzoate

KAN0438757 is a potent and selective inhibitor of the metabolic kinase PFKFB3 with an IC50 value of 0·19μM

ChemicalCAS1451255-59-6MW447.43FormulaC21H18FNO7S
CAS number
1451255-59-6
Molecular weight
447.43
Formula
C21H18FNO7S
Solubility
DMSO: 130 mg/mL (290·55 mM)
InChIKey
QRDFCYMUXHUTCS-UHFFFAOYSA-N
Catalogue number
GC36383
Brand
GLPBIO
Computed properties PubChem CID 71586631 · XLogP 3.2 · TPSA 142 Ų · H-bond donors 4
XLogP
3.2
TPSA
142 Ų
H-bond donors
4
H-bond acceptors
9
Rotatable bonds
8
Heavy atoms
31

SMILES C1=CC(=CC(=C1)S(=O)(=O)NC2=CC(=C(C=C2)C(=O)OCCO)O)C3=C(C=CC(=C3)F)O

Computed descriptors from PubChem (CID 71586631), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.