GC36351
Itacitinib adipate
Also known as 2-[1-[1-[3-fluoro-2-(trifluoromethyl)pyridine-4-carbonyl]piperidin-4-yl]-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile;hexanedioic acid
Itacitinib adipate is an orally bioavailable and selective JAK1 inhibitor which has been tested for efficacy and safety in a phase II trial in myelofibrosis
ChemicalCAS1334302-63-4MW699.66FormulaC32H33F4N9O5
- CAS number
- 1334302-63-4
- Molecular weight
- 699.66
- Formula
- C32H33F4N9O5
- Solubility
- DMSO： ≥ 137·5 mg/mL (196·52 mM)
- InChIKey
- CEGWJIQFBNFMHQ-UHFFFAOYSA-N
- Catalogue number
- GC36351
- Brand
- GLPBIO
Computed properties PubChem CID 67390313 · TPSA 194 Ų · H-bond donors 3 · H-bond acceptors 15
- TPSA
- 194 Ų
- H-bond donors
- 3
- H-bond acceptors
- 15
- Rotatable bonds
- 10
- Heavy atoms
- 50
SMILES C1CN(CCC1N2CC(C2)(CC#N)N3C=C(C=N3)C4=C5C=CNC5=NC=N4)C(=O)C6=C(C(=NC=C6)C(F)(F)F)F.C(CCC(=O)O)CC(=O)O
Computed descriptors from PubChem (CID 67390313), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il