Loading...
Chemical structure of INCB 3284

GC36306

INCB 3284

Also known as N-[2-[[(3R)-1-[4-hydroxy-4-(6-methoxy-3-pyridinyl)cyclohexyl]pyrrolidin-3-yl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamide

INCB 3284 is a potent, selective and orally bioavailable human CCR2 antagonist, inhibiting monocyte chemoattractant protein-1 binding to hCCR2, with an IC50 of 3·7 nM

ChemicalCAS887401-92-5MW520.54FormulaC26H31F3N4O4
CAS number
887401-92-5
Molecular weight
520.54
Formula
C26H31F3N4O4
Solubility
DMSO： ≥ 83·3 mg/mL (160·03 mM)
InChIKey
NXZNYBUBXWWKCP-JMOWIOHXSA-N
Catalogue number
GC36306
Brand
GLPBIO
Computed properties PubChem CID 11527661 · XLogP 2.8 · TPSA 104 Ų · H-bond donors 3
XLogP
2.8
TPSA
104 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
7
Heavy atoms
37

SMILES COC1=NC=C(C=C1)C2(CCC(CC2)N3CC[C@H](C3)NC(=O)CNC(=O)C4=CC(=CC=C4)C(F)(F)F)O

Computed descriptors from PubChem (CID 11527661), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.