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Chemical structure of gamma-secretase modulator 2

GC36108

gamma-secretase modulator 2

Also known as 6-fluoro-3-[4-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]-1-(2,2,2-trifluoroethyl)-4,5-dihydro-3H-1-benzazepin-2-one

gamma-secretase modulator 2 is a potent and selective γ-secretase modulator for treatment of Alzheimer's disease

ChemicalCAS1093978-89-2MW514.47FormulaC25H22F4N6O2
CAS number
1093978-89-2
Molecular weight
514.47
Formula
C25H22F4N6O2
Solubility
DMSO : 100 mg/mL (194·37 mM; Need ultrasonic)
InChIKey
AAHNBILIYONQLX-UHFFFAOYSA-N
Catalogue number
GC36108
Brand
GLPBIO
Computed properties PubChem CID 59472574 · XLogP 4.3 · TPSA 78.1 Ų · H-bond donors 0
XLogP
4.3
TPSA
78.1 Ų
H-bond donors
0
H-bond acceptors
9
Rotatable bonds
5
Heavy atoms
37

SMILES CC1=CN(C=N1)C2=C(C=C(C=C2)C3=CN(N=N3)C4CCC5=C(C=CC=C5F)N(C4=O)CC(F)(F)F)OC

Computed descriptors from PubChem (CID 59472574), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.