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Chemical structure of Foxy-5

GC36073

Foxy-5

Also known as (2S)-2-[[(2S)-4-carboxy-2-[[(2R)-2-[[2-[[(2S)-3-carboxy-2-[[(2S)-2-formamido-4-methylsulfanylbutanoyl]amino]propanoyl]amino]acetyl]amino]-3-sulfanylpropanoyl]amino]butanoyl]amino]-4-methylpentanoic acid

Foxy-5, a WNT5A agonist, is a mimicking peptide of WNT5A which is a non-canonical member of the Wnt family· Foxy-5 triggers cytosolic free calcium signaling without affecting β-catenin activation and it impairs the migration and invasion of epithelial cancer cells· Foxy-5 effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model

ChemicalCAS881188-51-8MW694.77FormulaC26H42N6O12S2
CAS number
881188-51-8
Molecular weight
694.77
Formula
C26H42N6O12S2
Solubility
Soluble in DMSO
InChIKey
WFZPJYYCTSHDJI-ATIWLJMLSA-N
Catalogue number
GC36073
Brand
GLPBIO
Computed properties PubChem CID 44628955 · XLogP -1.6 · TPSA 313 Ų · H-bond donors 10
XLogP
-1.6
TPSA
313 Ų
H-bond donors
10
H-bond acceptors
14
Rotatable bonds
23
Heavy atoms
46

SMILES CC(C)C[C@@H](C(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CS)NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCSC)NC=O

Computed descriptors from PubChem (CID 44628955), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.