Loading...
Chemical structure of Episilvestrol

GC35998

Episilvestrol

Also known as methyl (1R,2R,3S,3aR,8bS)-6-[[(2S,3R,6R)-6-[(1S)-1,2-dihydroxyethyl]-3-methoxy-1,4-dioxan-2-yl]oxy]-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate

Episilvestrol is a derivative of silvestrol, isolated from the fruits and twigs of Aglaia silvestris, and is a specific eIF4A-targeting translation inhibitor, with antitumor activity

ChemicalCAS697235-39-5MW654.66FormulaC34H38O13
CAS number
697235-39-5
Molecular weight
654.66
Formula
C34H38O13
Solubility
Soluble in DMSO
InChIKey
GVKXFVCXBFGBCD-JRPGFILLSA-N
Catalogue number
GC35998
Brand
GLPBIO
Computed properties PubChem CID 11467934 · XLogP 1.6 · TPSA 172 Ų · H-bond donors 4
XLogP
1.6
TPSA
172 Ų
H-bond donors
4
H-bond acceptors
13
Rotatable bonds
11
Heavy atoms
47

SMILES CO[C@H]1[C@@H](O[C@H](CO1)[C@H](CO)O)OC2=CC3=C(C(=C2)OC)[C@@]4([C@@H]([C@@H]([C@H]([C@@]4(O3)C5=CC=C(C=C5)OC)C6=CC=CC=C6)C(=O)OC)O)O

Computed descriptors from PubChem (CID 11467934), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.