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Chemical structure of Cenisertib

GC35651

Cenisertib

Also known as (1S,2S,3R,4R)-3-[[5-fluoro-2-[3-methyl-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide

Cenisertib (AS-703569) is an ATP-competitive multi-kinase inhibitor that blocks the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5 and FLT3· Cenisertib induces major growth-inhibitory effects by blocking the activity of several different molecular targets in neoplastic mast cells (MC)· Cenisertib inhibits tumor growth in xenograft models of pancreatic, breast, colon, ovarian, and lung tumors and leukemia

ChemicalCAS871357-89-0MW451.54FormulaC24H30FN7O
CAS number
871357-89-0
Molecular weight
451.54
Formula
C24H30FN7O
Solubility
DMSO： 250 mg/mL (553·66 mM)
InChIKey
KSOVGRCOLZZTPF-QMKUDKLTSA-N
Catalogue number
GC35651
Brand
GLPBIO
Computed properties PubChem CID 11569967 · XLogP 3.2 · TPSA 99.4 Ų · H-bond donors 3
XLogP
3.2
TPSA
99.4 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
6
Heavy atoms
33

SMILES CC1=C(C=CC(=C1)NC2=NC=C(C(=N2)N[C@@H]3[C@@H]4C[C@H]([C@@H]3C(=O)N)C=C4)F)N5CCN(CC5)C

Computed descriptors from PubChem (CID 11569967), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.