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Chemical structure of CADD522

GC35576

CADD522

Also known as 3-[(3,4-dichlorophenyl)carbamoyl]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid

CADD522 is a RUNX2-DNA binding inhibitor (downregulates RUNX2-mediated transcription of downstream target genes), with an IC50 of 10 nM· CADD522 inhibits primary tumor growth and experimental metastasis of tumor cells in the lungs of immune-compromised mice· CADD522 can be used in study of cancer

ChemicalCAS199735-88-1MW326.17FormulaC15H13Cl2NO3
CAS number
199735-88-1
Molecular weight
326.17
Formula
C15H13Cl2NO3
Solubility
DMSO： 250 mg/mL (766·47 mM)
InChIKey
YSDNWNOGHQYWPK-UHFFFAOYSA-N
Catalogue number
GC35576
Brand
GLPBIO
Computed properties PubChem CID 2834870 · XLogP 2.9 · TPSA 66.4 Ų · H-bond donors 2
XLogP
2.9
TPSA
66.4 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
3
Heavy atoms
21

SMILES C1C2C=CC1C(C2C(=O)NC3=CC(=C(C=C3)Cl)Cl)C(=O)O

Computed descriptors from PubChem (CID 2834870), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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