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Chemical structure of BPR1K871

GC35545

BPR1K871

Also known as 1-(3-chlorophenyl)-3-[5-[2-[[7-[3-(dimethylamino)propoxy]quinazolin-4-yl]amino]ethyl]-1,3-thiazol-2-yl]urea

BPR1K871 is a potent and selective dual FLT3/AURKA inhibitor with IC50s of 19 nM and 22 nM for FLT3 and AURKA, respectively, acts as a preclinical development candidate for anti-cancer therapy

ChemicalCAS2443767-35-7MW526.05FormulaC25H28ClN7O2S
CAS number
2443767-35-7
Molecular weight
526.05
Formula
C25H28ClN7O2S
Solubility
DMSO： 125 mg/mL (237·62 mM)
InChIKey
MMVLETOTGHDVPQ-UHFFFAOYSA-N
Catalogue number
GC35545
Brand
GLPBIO
Computed properties PubChem CID 126970666 · XLogP 4.8 · TPSA 133 Ų · H-bond donors 3
XLogP
4.8
TPSA
133 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
11
Heavy atoms
36

SMILES CN(C)CCCOC1=CC2=C(C=C1)C(=NC=N2)NCCC3=CN=C(S3)NC(=O)NC4=CC(=CC=C4)Cl

Computed descriptors from PubChem (CID 126970666), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.